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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6067adad95b962522c748032c096e3aa72e403fe47924ffcf37857eb802a9242' 
  AND token = 'Ds5x2sjwrIrosa6B0XV+SyRJk0esrBsyuIMqRFw4EYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}