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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5f52a394769f1392ee3fdb93c068d7660f4830251c38545c2bdc5f356b2d1c' 
  AND token = 'hQBDh20ybywM51+LGl398zlPCWod3nUJxAgqj5GqCoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}