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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e960462af912f5854d9bc97ff3747f26914fd1c0ae07d7fb2d083254643e10f1' 
  AND token = 'Yde22e2yQ6Nx0HCg3TNio62PYpUM8CjPcAS6IZ2vZ/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}