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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5018597ef33012388d032218322cc7689e2bea08448827d63ec9602728b5c37' 
  AND token = 'UxHvM7tiXUcszDjwYAO9H+2oSgtz/Ysmi0co+SwdYNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}