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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35cad49fc099112c5d4d61dcd702e478fa37c7b426d6f994073483d693bed0e' 
  AND token = 'YdIK+oVsAemhbR+uf5ejzZlTOTaCFO4K2xW0MATnhJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}