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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ad20c8584ce812ac8b22a9d4e25bfb1134414901664d13b500d42ab80681a0' 
  AND token = 'UnpLi/kOaW9mC/mkBSBcY/c+tEdyghfLHhJDvj+80CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}