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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5480100c1a9bd3eaf1505f01d0b5ce035f0754ddd8b9be29e33335cde5cb6515' 
  AND token = 'libD7v5dxm4Cwb2otwfLWmLYuQULKCuQlBe4AKWDwy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}