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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d24d0243e61558f9862526e3126f601c18c27ed14d640462165f8b5554124f7' 
  AND token = 'hNTaBQ/GZ70Tg5+ERxlxKj0WjT9i3t3RWXeTcLoADto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}