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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9730ac675e2be41c7b02dbcb0b69267d9aa9f399ab1296d070cf948cb7e77aae' 
  AND token = 'zpcqxYO+m2L1R9bEHByyqJiVrjQdENfcHVygJqMaGLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}