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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0203aa793387bd3e9f8ed95c7e1f4765fa239abea4deacf0053e199f8cb0b9' 
  AND token = 'kFO2Uq/Fro8hxF9GowfjbJPs0VeE5i+HPMI6+YOGSfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}