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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b45da306853dd6e0ca2390389869a8b70cbceeb328bd50562a840ce6c62c46' 
  AND token = '7TCoQksBo+TObeOGvoMe8itSG1UqkqQbeoc8uf5QR68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}