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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec81820b4fbfccf3f64d3770a770ad4bbf7fe90f88d12c2ee739a19611a3ea4a' 
  AND token = 'Hlb2XQCe1pmLZ3i7+Ue8WgvyfBJhThN5k4MEgFgOZVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}