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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1c352309f7a59170380d11e92df9a2c497a2f592a8bc8d66f7494e8bb63b40' 
  AND token = 'PgOtRWE0lUk8do/kR5kneO7ZITEQS9h5XEBFBLbGNe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}