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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a6672f8f3347332c8a2845638e998d187067516adc63e7bd6b7e14e525b0fa' 
  AND token = 'ngNY+rWlmQ6BwYe22GSeO98tagPz/rlFX3QDnTgLOIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}