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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1242cb4afeee08b3daa197e9038022c375d6fc0a3e0c41f692c3128dcdd4acd4' 
  AND token = 'p44ZmpLnIbVXUOIepoHgzDVUHG3ckVMU3hnFbS3OLHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}