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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cdfdf1ec2ea973b267c3c04cb8bcfa018bfa9117a26703cb3a9ba408cce5f8c' 
  AND token = 'nD5BZC6ZaODkG0gApq+ZEr9JRX2X7FtKikBVUO2blCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}