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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3839959949c36d830991fe82c7c8edcf74d2408b02b992244a72c6a1a2725097' 
  AND token = 'ev/dOUHTKKQrRblXYzazfQn0Cx4+IWl6F0rCxWy8AY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}