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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3725a7a0b5af3c29e716e3eacb58abf3d1936ad175e1f503e13a111ee26703b' 
  AND token = 'Xg904dHZK8HYj+uKxFEfeta9CxwzLSc1P/NmB58tV58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}