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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819d362943f05c75606c80dc6b0e40f718b9744b39fd6dafd1b3b737d50b2326' 
  AND token = 'IT6iKxeCvxy335HncO6uA9QozFtIp0ZJus8Gyzvr8js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}