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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb78e9d88ca343d6e8fac0a8a35a357ff4b8183c281763031ebcfffcfd95b81f' 
  AND token = 'e+Z7l7P4CHcZLDxrG/bAuufiEaP0eazRgmrENprFWZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}