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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb763d6e2a6d8750498240b4f6f946a04309e231cb0ebf4844c5e54084d0e179' 
  AND token = 'GJDh0LTR1Y6RoLQEHVZXkPEn7e4ZvXiVpGty3NJfAbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}