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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d6efc6e77c6c341d239520bb32828399238fe26d4337535cde5b4e7620be05' 
  AND token = 'EdCeku23WlTPPzQ/yC173bVP9CbAJSLJ/kO/xkmXaC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}