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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e645d550131db657d087334e951e09ed209d2270bcdc723de1ef3d04d805b99' 
  AND token = '4OcxD9LQqZWxySK3MGJyuM7D4pKqrrYqoVac3MT3Ad4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}