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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610d5f0eb1879505464c1d24f9e158135c91c0d6c77c609095a1be223a7636e6' 
  AND token = '+aArm+yXNu+UMKCWQVBmY8uHuBeuoS2WlAgyQoAwHvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}