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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47e3f42649854e3e391e48081ec5b02df9012bc0be7d72136dbd683f884bec08' 
  AND token = 'qPP9gPbIackds+VN2xBGavj+U3m992uvwLqXaEONq2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}