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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8ac3eb0b72c5bf95482256e3f2218f61b5b6b527c1c9148e928987ac12f1df' 
  AND token = 'kPz0RAkrye2w0qObOvTDtlHeM22deG5u85DlNzAQQk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}