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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7615e1086c72dbb4eee5a3b06247eb6311eead0acaae36efa3246f483ebe65c1' 
  AND token = 'PCJ2L4Gw9+QH/6rJI+rLB+6S/sYHo0f/DPneAE9I7uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}