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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb2b6d261f0d51cf4ac7af0fb092a3dfc9365dab8567e3a12684a8d262abc67c' 
  AND token = 'LOFNY/rtAU0U8QkQ/TbMFUC6bUn9P5YfYxguSctzjkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}