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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7a8dfbb3688d23c8c3a0eaa2c7346a815def8e27a3dc27d73c92bdadef2790' 
  AND token = 'jiOyV9RqF3adwQhKxIT4wdq8VOx77PzOm8u5nRC5f14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}