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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22b785144350ec2cc2dfdbb95543c41c2460c68623a2ab6b2aa38ba6d77cab7' 
  AND token = 'I1xmjl905TbkGNXRrYnK4SxfQs6JgGpZuUN3ykCTL28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}