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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f524e1d678f0526ada2e6fe72d4a021687d794a6bf31cb5384f3bad76b734aa1' 
  AND token = 'V4AeWCH/YDldXSpRO22xW0c/PlsM1TBAjtx0ZYpi938=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}