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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '551f163acc7ade9db828d996171d87a49bc690610f8a56c53b755e7302c342fe' 
  AND token = '+SrG95hCnV9N8aMopBXSuAzg+lPav2cOAze1RkhYASI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}