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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec46d047538a28499bca20f787e0ef7b7bef35628725f84bdba5081b338da0bc' 
  AND token = 'WvK52t1Le4/ijyJf1cQak3OY/pGTV0YnIg9rEqYP/9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}