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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6305fe08022bf40306fd1cce2859ef4871f721c9d536ce53f62c839d1b69b4a4' 
  AND token = 'sO93BZOyQYjPpuMIivURsA2RkWNqrg2e5qneTrDcPmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}