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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b373d159b7a60c96bb1a0542ce278aecd092081b974db6b539fc9f481756f648' 
  AND token = 'esfRFNTCA1hIn5RTOMKVYPwh3zBYNgOs53eOuCsg6IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}