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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3f6aa68180f14c7cd9df4c563d33eee2f3df6af1a9471021890d122281672b' 
  AND token = 'xPafDmr6de4Sh2fSKQwYZIiSd+cgPquwAyDC+RRDiUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}