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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1fea82eb124f541403df0808b163f464e4966a0e848659cec21214153d3f4d' 
  AND token = '4k4rDmCwHhUZCrRxpFusVHSEzqMOuzL+xfg+cTTctKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}