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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a406136def2cfc5446fdc07b52f202f08f56113053bb4e584290bb81b542ec65' 
  AND token = 'UF0JxVQH3JK8Lfw3sDtz/Ysaxi8rmDX+YbI71bsVHf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}