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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50dfcd8239c87f5ae69d2ab96a24419c86a184c43ad1c09ed97610ccb8431220' 
  AND token = 'OcMMU6Ef8zUVPJmzBKwBv/hCPy15jQoBi8zdi4zQyns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}