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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800e2a44ae54680d58fda3efa049a5da58fde16d238dd3eb7630f6588e63413e' 
  AND token = 'KdZvYv1gRrOtqfEpO9PLJRkDFlzhaMYF13WmV28m7Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}