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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca3d0875ed3cbe7123405407ee6d49774f37b13c4576c644f280d9570929951' 
  AND token = 'IbR/kWY42+PHixJfpcS7ordcNQOD+P9/5xAplXRx8I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}