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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89108e075aea58d3c5c1fd7660ce045dce6c96d0e87e3c5efcef891610e27bc' 
  AND token = '+SjTIyIYJ4rcuvZLzzi3vBh0pCVKJ2P0kBADtuSs/A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}