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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180ef2daf7d392d91a1441a5974cd11c4ef570238ec5236d9675a2107d296a98' 
  AND token = 'IlXou6jIZuI+gR6B2IZWMdHbK/c/cxWEy7HP6O7Zph4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}