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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3658023d77cc72be78fad69b04850a8f6659459c85aa05660da2f458489be6b' 
  AND token = 'jQK+yiv6PqPlAqLJ6AScBbXpssQGaPneFNQW4Rr7wmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}