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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8c1fd6c9b4ecb43301eb2ce61d04eba061d2968b147984614423c0103909ce' 
  AND token = 'MMzT8NsWNAg11f8Cg4Y1B3Irty76EniNoNGfKK8FfQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}