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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acea6a011b20e6b9fc900d7206e7f3e8b51332ef8a973799121b1de178e387c4' 
  AND token = 'NSJBpVUWmRImhldjQwU1F5EZwW2YkHedHs1ES4azgOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}