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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d38d1dd25f4f189b358784ddb04439ac11e86b0be2bb141a1027902b964aaa4' 
  AND token = 'O8N9l0B6jbW+Mz4kfAqrApo6pFp5ol6yZPBFZEsCfJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}