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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c76764f7d7df44d1fb8343922f8ce80de100afd4454514306033a181f9d6747' 
  AND token = 'zuCUBs1vVMisj+LYpsXHx5fZ31c4lao99PWdVq1eQ2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}