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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05dc70e83b6f3cc1836f85dfd83bd61d6fdbc5b4c6d520e4bc76017e81bf653' 
  AND token = 'PVmmrWBbr5rcHWBK8yGdA16mJEMM2h6LdZbATuFY7go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}