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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3685bc6a09ec74fa4867effcc5be2c3ac7099be4670293a03cd082759dbbe5' 
  AND token = '7JDu+dTDtzEPTJLAj4Nu0MZrQYHV7xXWwyPTuK5K6js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}